Rational Reagent Tactics for Optimizing Biomarker Analysis
Rational Reagent Tactics for Optimizing Biomarker Analysis
The selection or rational design of a linker to join fusion protein domains is an important, under-explored area in recombinant fusion protein technology
Background
Sourcing and applying multiple proteins into a specific biomarker assay involves a variety of moving pieces. Particularly during discovery stage research, where molecules of interest are constantly changing relative to hit identification. In other words, protein reagents play a significantly underrated role in developing early assays for biomarker analysis.
This article explores key material components and common oversight in recombinant protein approaches to help demonstrate factors effecting assay design. Additionally, we present a set of rational tactics for optimizing biomarker analysis through the procurement and criteria of laboratory/assay reagents.
Topics Covered
Insight on various aspects of the biomarker workflow, such as:
- Expression Hosts
- Tag/labeling
- Qualifying quality
- Critical reagents development relative to vendor consistency
Take the next step in optimizing your biomarker analysis.
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