Information plays a structural role in scientific research. At kbDNA, we perceive information as the most valuable material any organization can offer. That is why we dedicate our efforts to continuously providing novel, relevant data and insight to all researchers. Our pieces present organizational theories via opinion-editorials and trend analysis white papers. Technical notes, protocols and figures are all generated straight from the lab team to support design of experiments and application technique. The kbDNA Publishing Lab is designed to bridge research labs with the often-unfamiliar knowledge of the manufacturing lab that could be a valuable resource.
Multi-protein complexes (MPCs) play a crucial role in signaling. Blue native polyacrylamide gel electrophoresis (BN-PAGE) can be used for one-step isolation of MPCs from biological membranes/organelles and total cell and tissue homogenates under native conditions.
How natures molecules flow in bioresearch
In this piece, we present a series of protocols that suggest optimal preparation standards during the process of spotting and arraying microarrays relative to epoxy, aldehyde, and amine coated slides.
See the full list of in-house DNA Compounds used in our synthesis
See the full list of in-house DNA Modifiers used in our synthesis
See the full list of in-house RNA Compounds used in our synthesis
See the full list of in-house RNA Modifiers used in our synthesis
See the full list of in-house Reagents for Nucleic Acid Chemistry used in our synthesis
See the full list of in-house Amidites used in our synthesis
REFERENCE PROTEINS AS MOLECULAR-WEIGHT STANDARDS
Key takeaways from our experience building and advancing a reagent-specific search tool followed by our decision to drop the entire approach. In this editorial we provide helpful insight about the limitations of search functionality and the relevant information to consider when sourcing your next recombinant protein.
To further bridge the gap between designing a DNA or RNA sequence and the process of synthesizing it - this review offers a fundamental break-down of the core modifications that help support novel synthesis.
As CRISPR continues to innovate our lab methods and dominate our news feeds; its issues with off-targeting continue to limit downstream potential. Progress may be moving at a less favorable pace, but recent methods in novel modifications to the guide RNA (gRNA) structure may provide the necessary traction to move toward the right solutions.
A helpful guide for the variety of different protein tags - trending in recent growth
Understanding the back-end phenomenon of commercial reagents and the factors limiting their success in ecommerce.
It always seems like it’s raining recombinant proteins, until an experiment requires a difficult target. Then it just seems like an endless loop of identical catalogs from different companies. This has been a growing source of frustration for both manufacturers and researchers. Read our break-down about the difficult-to-express situation and what technology we believe bring hope to solutions...
A guide to modifying sequences for synthesis
Discussing current progress in oligonucleotides and why synthesis technology will play a key role toward future innovation
Learn and execute the methods involved in one of the most innovative approaches of synthetic biology
Review of the technical components that drive attachment chemistry in nucleotide synthesis
Developing a bio-website and the reqarding irony in failure throughout the process
Bootstrapping a biotech and questioning the trend of reagent supplier surplus