Nucleotide Synthesis

Manufacturing is in the Genes

Experience and credibility play significant roles in bio scientific research. ChemGenes reagents have been tried and true for decades, contributing non-stop innovations to improve coupling efficiency and the structural capabilities of automated synthesis. Their proven quality and expertise make them not only the most qualified, but also the best partner to compliment kbDNA’s synthesis platform..

Patents & Trademarks

• 2’-O-Methyl, Ethyl phosphoramidite, patent #: US 6,015,886.
• 2’-O-Methyl patent, patent #: US 5,525,719.
• 3’-O-Methyl patent #: US 5,525,719.
• 2’-O-Propargyl modified, patent #: US 5,744,595.
• 3’-O-Propargyl modified Amidites & Solid Supports, patent #: US 5,744,595.
• 2’-Ara-O-methyl amidites, Patent #: US 20120149888.
• Reverse RNA synthesis, patent App #: WO 2011103468.
• Dithiolane based thiol modifier, patent Provisional application #: PCT61/79585.
• Oligonucleotide Labeling-Cycloaddition Reaction, Patent #: US 20120058476.
• Modifications of antimetabolite gemcitabine for incorporation in CpG oligonucleotides, Patent #: US 20110040082
• N6-Trimethyl-L-Lysine & derivative, their therapeutic uses, Patant #: US 20110166230; US 20110166231; US 20110166379; US 20110166380