TFPI-2

Gene Synonyms:

Protein Names:

Organism:

Homo sapiens (Human)

Mass (kDa):

26934

Length (aa):

235

Sequence:

MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF

Proteomics (Proteome ID):

Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5)

Proteomics (Chromosome):

UP000005640

Mass Spectrometry:

N/A

Function [CC]:

May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. {ECO:0000269|PubMed:7872799}.

Metal Binding:

N/A

Site:

SITE 46 47 Reactive bond. {ECO:0000250}.; SITE 107 108 Reactive bond. {ECO:0000250}.; SITE 168 169 Reactive bond. {ECO:0000250}.

Tissue Specificity:

Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.

Disease:

N/A

Mutagenesis:

N/A

Name:

Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5)

Class:

Subcategory:

Recombinant

Source:

Species:

Human

Amino Acid Sequence:

Tag:

Format:

Lyophilized

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

pH:

7.4-7.5

NaCl:

Null

EDTA:

Null

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Inquire

Validated:

RP-HPLC

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.