CTXB

Gene Synonyms:

Protein Names:

Organism:

Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

Mass (kDa):

13957

Length (aa):

124

Sequence:

MIKLKFGVFFTVLLSSAYAHGTPQNITDLCAEYHNTQIYTLNDKIFSYTESLAGKREMAIITFKNGAIFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAISMAN

Proteomics (Proteome ID):

Cholera enterotoxin subunit B (Cholera enterotoxin B chain) (Cholera enterotoxin gamma chain) (Choleragenoid)

Proteomics (Chromosome):

UP000000584

Mass Spectrometry:

N/A

Function [CC]:

The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.

Metal Binding:

N/A

Site:

N/A

Tissue Specificity:

N/A

Disease:

N/A

Mutagenesis:

MUTAGEN 78 78 H->A: Loss of toxicity.

Name:

Cholera enterotoxin subunit B (Cholera enterotoxin B chain) (Cholera enterotoxin gamma chain) (Choleragenoid)

Class:

Subcategory:

Recombinant

Source:

Species:

Vibrio cholerae serotype O1

Amino Acid Sequence:

Tag:

Format:

Lyophilized

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

pH:

7.4-7.5

NaCl:

Null

EDTA:

Null

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Inquire

Validated:

RP-HPLC

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.