Cystatin S

Recombinant ID:

3284

Request Datasheet

Gene of Interest

Gene Synonyms:

CST4

Protein Names:

Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

16214

Length (aa):

141

Sequence:

MARPLCTLLLLMATLAGALASSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWEDRMSLVNSRCQEA

Proteomics (Proteome ID):

Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1)

Proteomics (Chromosome):

UP000005640

Mass Spectrometry:

Mass=14175.8569; Mass_error=0.0564; Method=Electrospray; Range=21-141; Evidence={ECO:0000269|PubMed:20189825}; Mass=14255.8567; Mass_error=0.0899; Method=Electrospray; Range=21-141; Note=Monophosphorylated at Ser-23, also called form S1.; Evidence={ECO:0000269|PubMed:20189825}; Mass=14335.811; Mass_error=0.0775; Method=Electrospray; Range=21-141; Note=Diphosphorylated at Ser-21 and Ser-23, also called form S2.; Evidence={ECO:0000269|PubMed:20189825};

Function [CC]:

This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.

Metal Binding:

N/A

Site:

SITE 32 32 Reactive site.

Tissue Specificity:

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. {ECO:0000269|PubMed:20189825}.

Disease:

N/A

Mutagenesis:

N/A

Reagent Data

Name:

Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1)

Class:

Subcategory:

Recombinant

Molecular Weight:

Source:

Species:

Human

Amino Acid Sequence:

Inquire

Tag:

Format:

Lyophilized

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

pH:

7.4-7.5

Stabilizers

NaCl:

Null

Metal Chelating Agents

EDTA:

Null

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Inquire

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.