B18R

Gene Synonyms:

Protein Names:

Organism:

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))

Mass (kDa):

40732

Length (aa):

351

Sequence:

MTMKMMVHIYFVSLLLLLFHSYAIDIENEITEFFNKMRDTLPAKDSKWLNPACMFGGTMNDIAALGEPFSAKCPPIEDSLLSHRYKDYVVKWERLEKNRRRQVSNKRVKHGDLWIANYTSKFSNRRYLCTVTTKNGDCVQGIVRSHIRKPPSCIPKTYELGTHDKYGIDLYCGILYAKHYNNITWYKDNKEINIDDIKYSQTGKELIIHNPELEDSGRYDCYVHYDDVRIKNDIVVSRCKILTVIPSQDHRFKLILDPKINVTIGEPANITCTAVSTSLLIDDVLIEWENPSGWLIGFDFDVYSVLTSRGGITEATLYFENVTEEYIGNTYKCRGHNYYFEKTLTTTVVLE

Proteomics (Proteome ID):

Soluble interferon alpha/beta receptor B18 (B18)

Proteomics (Chromosome):

UP000000344

Mass Spectrometry:

N/A

Function [CC]:

Counteracts the antiviral effects of host IFN-alpha/beta. Acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor. {ECO:0000269|PubMed:19073732}.

Metal Binding:

N/A

Site:

N/A

Tissue Specificity:

N/A

Disease:

N/A

Mutagenesis:

N/A

Name:

Soluble interferon alpha/beta receptor B18 (B18)

Class:

Subcategory:

Recombinant

Source:

Species:

Vaccinia Virus

Amino Acid Sequence:

Tag:

Format:

Lyophilized

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

pH:

7.4-7.5

NaCl:

Null

EDTA:

Null

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Inquire

Validated:

RP-HPLC

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.