Oncostatin M
Recombinant ID:
3629
Gene of Interest
Gene Synonyms:
OSM
Protein Names:
Oncostatin-M (OSM)
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
28484
Length (aa):
252
Proteomics (Proteome ID):
Oncostatin-M (OSM)
Proteomics (Chromosome):
UP000005640
Sequence:
MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRKGKRLMTRGQLPR
Analysis Summary:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250, ECO:0000269|PubMed:1542792, ECO:0000269|PubMed:1542793}.,Chain (1); Disulfide bond (2); Glycosylation (2); Helix (10); Mutagenesis (6); Natural variant (1); Propeptide (1); Signal peptide (1); Turn (1)
Reagent Data
Name:
Oncostatin-M (OSM)
Subcategory:
Recombinant
Amino Acid Sequence:
Inquire
Species
Human
Tag:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Buffer Volume
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Purity:
> 98%
Determined:
SDS-PAGE
Stained:
Assay (Variable)
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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