LILRB4

Recombinant ID:

3464

Gene of Interest

Gene Synonyms:

Lilrb4;Gp49b

Protein Names:

Leukocyte immunoglobulin-like receptor subfamily B member 4 (Mast cell surface glycoprotein Gp49B) (CD antigen CD85k)

Accession Data

Organism:

Mus musculus (Mouse)

Mass (kDa):

37544

Length (aa):

335

Metal Binding:

Pending Verification

Proteomics (Proteome ID):

Leukocyte immunoglobulin-like receptor subfamily B member 4 (Mast cell surface glycoprotein Gp49B) (CD antigen CD85k)

Proteomics (Chromosome):

UP000000589

Disease:

N/A

Mutagenesis:

N/A

Sequence:

MIAMLTVLLYLGLILEPRTAVQAGHLPKPIIWAEPGSVIAAYTSVITWCQGSWEAQYYHLYKEKSVNPWDTQVPLETRNKAKFNIPSMTTSYAGIYKCYYESAAGFSEHSDAMELVMTGAYENPSLSVYPSSNVTSGVSISFSCSSSIVFGRFILIQEGKHGLSWTLDSQHQANQPSYATFVLDAVTPNHNGTFRCYGYFRNEPQVWSKPSNSLDLMISETKDQSSTPTEDGLETYQKILIGVLVSFLLLFFLLLFLILIGYQYGHKKKANASVKNTQSENNAELNSWNPQNEDPQGIVYAQVKPSRLQKDTACKETQDVTYAQLCIRTQEQNNS

Function [CC]:

Receptor for class I MHC antigens. Involved in the down-regulation of the immune response and the development of tolerance. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (By similarity). {ECO:0000250}.

Analysis Summary:

Alternative sequence (2); Chain (1); Disulfide bond (2); Domain (2); Glycosylation (2); Motif (2); Signal peptide (1); Topological domain (2); Transmembrane (1)

Reagent Data

Name:

Leukocyte immunoglobulin-like receptor subfamily B member 4 (Mast cell surface glycoprotein Gp49B) (CD antigen CD85k)

Subcategory:

Recombinant

Source:

HEK293

Species:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Determined:

SDS-PAGE

Purity:

> 98%

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

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